For a quick reference, the CDC has also published links to the evidence on its website.
For more detail, here follows a selection of some of the current scientific evidence for the safety and effectiveness of the whooping cough vaccine in pregnancy.

- Kharbanda, E. O., Vazquez-Benitez, G., Lipkind, H. S., Klein, N. P., Cheetham, T. C., Naleway, A., … & Nordin, J. D. (2014). Evaluation of the association of maternal pertussis vaccination with obstetric events and birth outcomes. JAMA, 312(18), 1897-19

- Morgan, J. L., Baggari, S. R., McIntire, D. D., & Sheffield, J. S. (2015). Pregnancy Outcomes After Antepartum Tetanus, Diphtheria, and Acellular Pertussis Vaccination. Obstetrics & Gynecology, 125(6), 1433-1438.

- Munoz, F. M., Bond, N. H., Maccato, M., Pinell, P., Hammill, H. A., Swamy, G. K., … & Baker, C. J. (2014). Safety and Immunogenicity of Tetanus, Diphtheria, and Acellular Pertussis Immunization During Pregnancy in Mothers and Infants: A Randomized Clinical Trial. Obstetrical & Gynecological Survey, 69(9), 517-519.

- Sukumaran, L., McCarthy, N. L., Kharbanda, E. O., Weintraub, E. S., Vazquez-Benitez, G., McNeil, M. M., … & Orenstein, W. A. (2015). Safety of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis and Influenza Vaccinations in Pregnancy. Obstetrics & Gynecology, 126(5), 1069-1074.

- Sukumaran, L., McCarthy, N. L., Kharbanda, E. O., McNeil, M. M., Naleway, A. L., Klein, N. P., … & Omer, S. B. (2015). Association of Tdap Vaccination With Acute Events and Adverse Birth Outcomes Among Pregnant Women With Prior Tetanus-Containing Immunizations. JAMA, 314(15), 1581-1587.

- Amirthalingam, G., Andrews, N., Campbell, H., Ribeiro, S., Kara, E., Donegan, K., … & Ramsay, M. (2014). Effectiveness of maternal pertussis vaccination in England: an observational study. The Lancet, 384(9953), 1521-1528.

- Dabrera, G., Amirthalingam, G., Andrews, N., Campbell, H., Ribeiro, S., Kara, E., … & Ramsay, M. (2014). A case-control study to estimate the effectiveness of maternal pertussis vaccination in protecting newborn infants in England and Wales, 2012–2013. Clinical Infectious Diseases, ciu821.





Page reviewed March 2018