Whooping cough vaccination in pregnancy; the evidence

For a quick reference, the CDC has also published links to the evidence on its website.

For more detail, here follows a selection of some of the current scientific evidence for the safety and effectiveness of the whooping cough vaccine in pregnancy.

Donegan; Safety of pertussis vaccination in pregnant women in UK- observational study


Kharbanda; Evaluation of the association of maternal pertussis vaccination with obstetric events and birth outcomes


Morgan; Pregnancy Outcomes After Antepartum Tetanus, Diphtheria, and Acellular Pertussis Vaccination


Munoz; Safety and Immunogenicity of Tetanus, Diphtheria, and Acellular Pertussis Immunization During Pregnancy in Mothers and Infants- A Randomized Clinical Trial


Sukumaran; Safety of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis and Influenza Vaccinations in Pregnancy


Sukumaran; Association of Tdap Vaccination With Acute Events and Adverse Birth Outcomes Among Pregnant Women With Prior Tetanus-Containing Immunizations


Amirthalingam; Effectiveness of maternal pertussis vaccination in England- an observational study


Dabrera; A case-control study to estimate the effectiveness of maternal pertussis vaccination in protecting newborn infants in England and Wales


Effectiveness of Prenatal Versus Postpartum Tetanus, Diphtheria, and Acellular Pertussis Vaccination in Preventing Infant Pertussis


Effectiveness of Vaccination During Pregnancy to Prevent Infant Pertussis




Page reviewed March 2018

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